HOME |　The Jikei University School of Medicine, Institute of Clinical Medicine and Research, WATABE Lab.

About Us

Watabe lab was newly established in April 2017. We are interested in the molecular and cellular mechanisms underlying adaptive behaviors which are modulated by emotional and motivational states.
Currently, we are recruiting Ph.D. students! If you are interested in our research and the lab, please feel free to contact us.
Click HERE for more info.

Latest informationarchive

Apr 2025: The paper on the joint research with Dr. Matsushima, Dr. Ohashi, and Dr. Kobayashi in The Jikei University School of Medicine is now published in The Journal of Clinical Investigation! Congratulations!
We have contributed to the behavioral investigation of pathological model mice. It is expected to be useful for developing treatments for lysosomal storage disorder.
“AAV expression of a blood-brain barrier-penetrating form of β-galactosidase normalises GM1 ganglioside storage in mice”
https://www.jci.org/articles/view/180724
　
Apr 2025: We are pleased to welcome Ms. Suda to our laboratory as a postdoctoral researcher.
We look forward to working together and advancing our research as a team!
In addition to the welcome and farewell party, we also enjoyed our annual cherry blossom viewing along the shores of Lake Teganuma.
Mar 2025: Dr. Toyama and Ms. Esaki have recently left our laboratory upon their retirement/graduation.
Through their research utilizing behavioral and electrophysiological approaches, they have made significant contributions to the development of our lab.
We would like to express our sincere gratitude for their dedicated efforts, and we wish them all the best in their future endeavors.
Mar 2025: The paper on the joint research with Dr. Pan and Dr. Takemoto-Kimura in Nagoya University is now published in Translational psychiatry! Congratulations!
We have contributed to the electrophysiological investigation of synaptic plasticity in the hippocampus of pathological model mice.
It is expected to be useful for developing treatments for Intellectual disability and neurodevelopmental disorder.
“A hyper-activatable CAMK2A variant associated with intellectual disability causes exaggerated long-term potentiation and learning impairments”
https://www.nature.com/articles/s41398-025-03316-4
　
Feb 2025: The paper on the joint research with Dr. Ageta-Ishihara in Toho University is now published in Cell Reports! Congratulations!
The mechanism of synaptic plasticity mediated by the septin cytoskeleton subunit SEPT3 has been clarified.
It is expected to be useful for elucidating the mechanism of memory formation and for developing treatments for neurological diseases.
“Septin 3 regulates memory and L-LTP-dependent extension of endoplasmic reticulum into spines”
https://www.cell.com/cell-reports/pdf/S2211-1247(25)00123-8.pdf
　
Jan 2025: Prof. Watabe has been appointed as the director of the Institute of Clinical Medicine and Research at the Jikei University School of Medicine.